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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186b9addd1f62570d061712d0bdaa7e95e2acd9cf1e8dbf732e6b4d26d5059d8' 
  AND token = 'wDgGbF/EolcmTPDJyWtPhzVjqWxrz9A3rQ4O37PfXQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}