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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33c1394d4367968cc8733c26848ed39d2e91e66003572e474500feb198bb6bc' 
  AND token = '6wzPZNMtmckF/WyQJRjQG7DKvNKMp671MEC3s46wn1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}