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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7789f8cacd05afd79a138e8edd900b03c20e6be0ee794e351aaee7bef54b7b51' 
  AND token = 'ZTus+b0T5fVuKgBJAvzdclarUpK9YSV4+9lpHL3XrdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}