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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72a92a81f231d9a3547919d551cb5f2447e3d741949188755d9937d744f09d7' 
  AND token = 'CX0ydO2g69wO20P6OcuuWsWJEZ7ZM2h+Duc0u4s06PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}